Jan-Gowth Chang Selected Research

Antihypertensive Agents (Antihypertensives)

9/2013	Modulating roles of amiloride in irradiation-induced antiproliferative effects in glioblastoma multiforme cells involving Akt phosphorylation and the alternative splicing of apoptotic genes.
1/2011	Amiloride modulates alternative splicing in leukemic cells and resensitizes Bcr-AblT315I mutant cells to imatinib.

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Jan-Gowth Chang Research Topics

Disease

58	Neoplasms (Cancer) 07/2023 - 11/2002
20	Hepatocellular Carcinoma (Hepatoma) 07/2023 - 02/2003
13	Carcinogenesis 01/2018 - 09/2003
11	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 05/2004
10	Lung Neoplasms (Lung Cancer) 01/2023 - 05/2003
9	Gout 12/2022 - 04/2013
9	Mouth Neoplasms (Oral Cancer) 01/2021 - 05/2003
9	Breast Neoplasms (Breast Cancer) 05/2020 - 11/2002
7	Squamous Cell Carcinoma of Head and Neck 09/2017 - 11/2002
6	Colonic Neoplasms (Colon Cancer) 01/2021 - 05/2004
6	Neoplasm Metastasis (Metastasis) 07/2019 - 11/2002
5	Infections 07/2023 - 09/2003
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021 - 05/2010
5	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2011 - 03/2002
4	Adenocarcinoma of Lung 01/2022 - 11/2014
4	Leukemia 09/2018 - 01/2003
4	Inflammation (Inflammations) 09/2018 - 11/2015
4	Endometrial Neoplasms (Endometrial Cancer) 05/2017 - 12/2005
4	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 04/2017 - 01/2008
4	Lymphatic Metastasis 03/2016 - 05/2004
3	Type 2 Diabetes Mellitus (MODY) 07/2020 - 05/2015
3	Thyroid Neoplasms (Thyroid Cancer) 12/2018 - 05/2003
3	Glioma (Gliomas) 09/2018 - 08/2016
3	Fibrosis (Cirrhosis) 01/2010 - 11/2007
3	beta-Thalassemia (Cooley's Anemia) 06/2008 - 08/2002
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 09/2003 - 05/2003
2	Hyperuricemia 01/2022 - 01/2018
2	Renal Cell Carcinoma (Grawitz Tumor) 05/2021 - 05/2018
2	Metabolic Diseases (Metabolic Disease) 01/2021 - 01/2018
2	Thalassemia 07/2020 - 07/2012
2	Rheumatoid Arthritis 09/2018 - 09/2014
2	Virus Diseases (Viral Diseases) 01/2018 - 01/2017
2	Myocardial Infarction 11/2017 - 11/2015
2	Carcinoma (Carcinomatosis) 01/2017 - 09/2003
2	Arthritis (Polyarthritis) 12/2016 - 11/2015
2	Lymphoma (Lymphomas) 05/2016 - 09/2010
2	Autoimmune Diseases (Autoimmune Disease) 05/2016 - 09/2014
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 03/2012 - 01/2003
2	Multiple Acyl Coenzyme A Dehydrogenase Deficiency 10/2011 - 05/2010
2	Nephrolithiasis 05/2011 - 01/2011
2	alpha-Thalassemia 02/2009 - 02/2003
2	Alzheimer Disease (Alzheimer's Disease) 01/2006 - 01/2003
2	Diabetes Mellitus 01/2006 - 11/2004
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2003 - 03/2002
1	Atherosclerosis 07/2023

Drug/Important Bio-Agent (IBA)

24	Proteins (Proteins, Gene)FDA Link 02/2023 - 11/2002
17	DNA (Deoxyribonucleic Acid)IBA 03/2020 - 02/2003
16	RNA (Ribonucleic Acid)IBA 07/2023 - 01/2011
12	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2006
9	Messenger RNA (mRNA)IBA 01/2023 - 12/2005
9	EnzymesIBA 09/2018 - 01/2003
7	Long Noncoding RNAIBA 01/2021 - 11/2014
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2022 - 11/2007
6	Phosphotransferases (Kinase)IBA 03/2021 - 05/2010
6	Histones (Histone)IBA 01/2017 - 01/2011
6	ErbB Receptors (EGF Receptor)IBA 09/2014 - 06/2009
5	Amiloride (Midamor)FDA LinkGeneric 01/2019 - 01/2011
5	Codon (Codons)IBA 09/2010 - 08/2002
4	MicroRNAs (MicroRNA)IBA 05/2021 - 07/2012
4	Protein Kinases (Protein Kinase)IBA 11/2015 - 01/2009
3	Oxygen (Dioxygen)IBA 01/2023 - 11/2004
3	CalciumIBA 01/2021 - 01/2011
3	Transcription Factors (Transcription Factor)IBA 09/2018 - 02/2009
3	NucleotidesIBA 05/2018 - 01/2003
3	Fatty Acids (Saturated Fatty Acids)IBA 10/2011 - 05/2005
3	Caveolin 1IBA 10/2004 - 09/2003
2	CytokinesIBA 07/2023 - 01/2010
2	RNA Splicing FactorsIBA 10/2020 - 01/2014
2	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 07/2020 - 09/2018
2	Oncogene Proteins (Oncogene Protein)IBA 01/2018 - 04/2006
2	Histone MethyltransferasesIBA 11/2017 - 01/2011
2	Cadherins (E-Cadherin)IBA 01/2017 - 11/2002
2	Nonmuscle Myosin Type IIAIBA 12/2016 - 10/2016
2	UbiquitinIBA 05/2016 - 12/2010
2	Epidermal Growth Factor (EGF)IBA 04/2016 - 09/2010
2	Formaldehyde (Formol)FDA Link 09/2014 - 10/2012
2	ParaffinIBA 09/2014 - 10/2012
2	Estrogens (Estrogen)FDA Link 09/2014 - 11/2002
2	Antihypertensive Agents (Antihypertensives)IBA 09/2013 - 01/2011
2	Fluorouracil (Carac)FDA LinkGeneric 05/2012 - 05/2004
2	Imatinib Mesylate (Gleevec)FDA Link 01/2011 - 12/2006
2	Arecoline (Arecolin)IBA 01/2011 - 07/2008
2	AlkaloidsIBA 01/2011 - 07/2008
2	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 09/2010 - 01/2009
2	Serum AlbuminIBA 11/2009 - 11/2007
2	IronIBA 10/2009 - 01/2006
2	glutathione S-transferase M1IBA 01/2006 - 11/2004
2	Coloring Agents (Dyes)IBA 10/2004 - 11/2002
2	Membrane Proteins (Integral Membrane Proteins)IBA 10/2004 - 09/2003
2	beta CateninIBA 10/2003 - 09/2003
2	Cytochrome P-450 CYP3AIBA 05/2003 - 03/2002
1	NF-kappa B (NF-kB)IBA 07/2023
1	LipidsIBA 07/2023
1	Cytokine Receptors (Cytokine Receptor)IBA 07/2023
1	VaccinesIBA 01/2023

Therapy/Procedure

14	Therapeutics 01/2023 - 12/2006
5	Drug Therapy (Chemotherapy) 09/2018 - 05/2004
2	Adjuvant Chemotherapy 09/2017 - 01/2011
2	Chronotherapy 12/2005 - 07/2005
1	Telescopes 07/2023